Clinical microbiology in detection and identification of emerging microbial pathogens: past, present and futureArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] 진단, [키워드] Antibody assays Antigen Bacterial pathogens change clinical clinical microbiology Clinical practice COVID-19 COVID-19 pandemic Critical Culture Diagnosis diagnostics Diseases evidenced Genomics Gram stain IMPROVE in vitro Infectious disease metabolomics microbial microbial infections Molecular biology MONITOR morphology nucleic acid nucleic acid amplification outcome pathogen detection Patient point of care progression proteomics Revolutionary transcriptomics transcriptomics. [DOI] 10.1080/22221751.2022.2125345 PMC 바로가기
Meta-analysis of the microbial biomarkers in the gut-lung crosstalk in COVID-19, community-acquired pneumonia and Clostridium difficile infectionsArticle Published on 2022-11-012022-11-15 Journal: Letters in Applied Microbiology [Category] 바이오마커, [키워드] applied Biomarker Biomarkers Candida catastrophic cause Classifier Clostridium Clostridium difficile community-acquired pneumonia correlation COVID-19 COVID-19 infection data set Diversity Escherichia Faecalibacterium Gut gut-lung axis Health healthy Infection interplay lung Lungs metagenome microbial microbiota Mortality normalized offer organs pandemic processed profile prognostic biomarker progression random random forest classifier. respiratory Staphylococcus the disease the gut-lung axis trauma [DOI] 10.1111/lam.13798 PMC 바로가기
Forty Years of Molecular Diagnostics for Infectious DiseasesArticle Published on 2022-10-192022-11-15 Journal: Journal of Clinical Microbiology [Category] 유전자 메커니즘, 진단, 치료기술, [키워드] amplification assumed Care coronavirus disease COVID-19 detect diagnostic diagnostic molecular microbiology diagnostics DNA DNA sequencing elapsed Factors Health in vitro Infectious disease Intersection knowledge Magnetic beads microbial molecular nucleic acid nucleic acids nucleotide nucleotide array pandemic pathophysiologic PCR Perspective point of care progression quantification Quantitative real-time quantitative PCR Sequencing syndromic panel. turn Year [DOI] 10.1128/jcm.02446-21 PMC 바로가기
Detection of SARS-CoV-2 in a dog with hemorrhagic diarrheaArticle Published on 2022-10-122022-11-15 Journal: BMC veterinary research [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome Affect African amino acid substitution analyzed Asymptomatic B.1.177 Bacterial Cell Ceuta characteristic circulation coronavirus COVID-19 detection diarrhea disease dog Dog COVID-19 excluded fecal gastrointestinal tract Genome Hemorrhagic Highland human SARS-CoV-2 human-to-animal transmission Ile402Val S protein substitution Infection Interaction intrinsic knowledge mapped microbial Microbiome MOST negative test Next-generation sequencing NGS North one health pandemic Pathogens pathology positive presenting RBD Receptor binding domain reported RT-PCR test S protein SARS-CoV-2 SARS-CoV-2 genome sequence Sequencing Spain Spanish suffered Terrier the S protein the spike protein USA variant viral loads viral variant virus West zoonosis. [DOI] 10.1186/s12917-022-03453-8 PMC 바로가기
The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemicArticle Published on 2022-09-302022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] 95% CI Admission aetiology Bacteria Bacterial Bergen categorical data Cohort cohorts Community community acquired community acquired pneumonia conducted containment measures COVID COVID-19 COVID-19 pandemic declined Electronic health record Epidemiology FilmArray pneumonia panel Fisher Haemophilus influenzae hospital Hospital admission hospitalized patient infection control less Lower respiratory tract Mann-Whitney measure microbial molecular testing outbreak pathogen Patient patients Pneumonia proportion Prospective Study reducing respiratory respiratory tract infection Respiratory tract infections SARS-CoV-2 SARS-CoV-2. significantly lower specimens Spread Staphylococcus aureus Streptococcus pneumoniae surveillance data t-test Trust variables virus was used [DOI] 10.1186/s12879-022-07732-5 PMC 바로가기
Nasopharyngeal Wash with Normal Saline Decreases SARS-CoV-2 Viral Load: A Randomized Pilot Controlled TrialArticle Published on 2022-09-272022-11-16 Journal: Canadian Respiratory Journal [Category] SARS, 변종, [키워드] 24 hour acute respiratory syndrome administration Admission Antigen baseline control group Controlled Controlled trial coronavirus COVID-19 disease cycle threshold decrease demonstrated determine Epidemiology Fatality rate Follow-up healthcare Hospitalization hospitalized patient increase in microbial morbidity N gene nasal washe nasopharyngeal Nasopharyngeal swab nasopharyngeal viral load non-COVID-19 patient normal outcome Pathogenesis Patient performed Pneumonia previous study Randomized reduce reduction in resource Saline SARS-CoV-2 significant decrease significantly the SARS-CoV-2 Treatment two group two groups variant Viral load Viral transmission was collected was performed with COVID-19 [DOI] 10.1155/2022/8794127 PMC 바로가기
SARS-CoV-2 Monitoring in Wastewater Reveals Novel Variants and Biomarkers of InfectionArticle Published on 2022-09-132022-11-15 Journal: Viruses [Category] SARS, 바이오마커, 변종, [키워드] Actinomycetaceae analysis Bacterial Biomarker Biomarkers changes in Combination Community correlation COVID-19 COVID-19 pandemic Diseases effective Epidemiology Infection Infectious disease information microbial microbial community monitoring mutants novel outbreak platform predict provide provided responses RNA SARS-CoV-2 Sequencing significant changes in significantly Spread spread of COVID-19 Surveillance unique variants variants of concern viral spread wastewater Wastewater-based epidemiology. [DOI] 10.3390/v14092032 PMC 바로가기
COVID-19 infection and transmission includes complex sequence diversityArticle Published on 2022-09-082022-11-15 Journal: PLoS Genetics [Category] SARS, 변종, 진단, [키워드] allele approach biallelic complex consensus sequence COVID-19 infection COVID-19 pandemic Delta Donor Evolution heterogeneity heterogeneous include Infection infections investigator Lineage majority microbial nucleotide change Occurrence omicron pandemic pathogen Patient polymorphism recipients reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 sequence sequence sequence variation Sequencing significantly SNP tested Transmission Transmission dynamics transmitted variant variants variants of concern viral genome whole genome [DOI] 10.1371/journal.pgen.1010200 PMC 바로가기
Zonulin, a marker of gut permeability, is associated with mortality in a cohort of hospitalised peruvian COVID-19 patientsArticle Published on 2022-09-062022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] 바이오마커, [키워드] age analysed baseline biochemical parameter Biomarker CCL5 Clinical data Cohort COVID-19 COVID-19 patient creatinine D-dimer value Deceased ELISA Gender Gut hospitalised hospitalised COVID-19 patients intestinal permeability inverse correlation long-COVID longitudinal study marker microbial microbial translocation Mortality multivariable analyses obesity outcome patients Peru positive correlation Prothrombin time quantification RANTES sandwich ELISA serum sample severe COVID-19 infections Variation various inflammatory diseases zonulin. [DOI] 10.3389/fcimb.2022.1000291 PMC 바로가기
Dynamic Alterations in the Respiratory Tract Microbiota of Patients with COVID-19 and its Association with Microbiota in the GutArticle Published on 2022-09-012022-11-15 Journal: Advanced Science [Category] 바이오마커, [키워드] Actinomyces alteration analyzed Bacteroide Biomarker Candida contributing to coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression determine Diagnosis disease Disease progression disease severity dynamic Enterococcus Fecal sample Gut gut microbiota ICU ICU Patients identify immune response Increases intensive care intensive care unit metagenome microbe microbial Microbiome microbiota mononuclear cell non-ICU pathway Patient patients patients with COVID-19 PBMC Peripheral blood positive correlation reduced respiratory respiratory microbiota. respiratory tract sequenced Significant significantly sputum Stage Streptococcus tract Treatment strategies with COVID-19 [DOI] 10.1002/advs.202200956 PMC 바로가기